Keyboard Options allows customization of shortcut keys (also called hotkeys) for many of the operations in 010 Editor. Access the Keyboard Options by clicking the 'Tools > Options...' menu option and selecting Keyboard from the list.
Select a command category from the Categories list to display a list of commands. All of the commands are organized by which menu they exist under in the main application window. Select a command from the Commands list on the right side of the dialog.
After a command is selected from the list, the default shortcut key will appear in the Original Shortcut field. Enter a new shortcut in the Custom Shortcut field. Note that the full shortcut must be typed into the field (for example, 'Ctrl+U' or 'Ctrl+Shift+U'). To reset the selected command to the original shortcut, click the Reset Key button.
Clicking the Reset button will reset all shortcut keys to their original values.